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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRF1
All Species:
20.61
Human Site:
Y501
Identified Species:
34.87
UniProt:
Q92994
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92994
NP_001510.2
677
73840
Y501
K
E
K
E
L
G
I
Y
K
E
H
K
P
K
K
Chimpanzee
Pan troglodytes
XP_510208
819
88957
Y643
K
E
K
E
L
G
I
Y
K
E
H
K
P
K
K
Rhesus Macaque
Macaca mulatta
XP_001098066
599
65136
K430
Y
K
E
H
K
P
K
K
S
C
K
R
R
E
P
Dog
Lupus familis
XP_548005
637
70371
K468
I
Y
K
E
H
K
P
K
K
S
C
K
R
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFK2
676
73781
Y500
K
E
K
E
L
G
I
Y
K
E
H
K
P
K
K
Rat
Rattus norvegicus
NP_001100231
686
74096
Y510
K
E
K
E
L
G
I
Y
K
E
H
K
P
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421405
681
75256
Y506
K
E
K
E
L
G
I
Y
K
E
H
K
P
K
K
Frog
Xenopus laevis
NP_001088063
660
73751
K488
E
E
R
I
A
K
E
K
E
L
G
I
Y
K
E
Zebra Danio
Brachydanio rerio
NP_956183
693
76806
T507
A
K
E
K
E
Q
G
T
Y
K
E
K
P
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650616
662
73627
R493
G
K
P
E
R
K
K
R
K
P
R
K
K
V
I
Honey Bee
Apis mellifera
XP_623775
648
73504
E479
E
K
E
E
G
K
P
E
K
K
R
R
R
T
T
Nematode Worm
Caenorhab. elegans
NP_495526
759
84015
R537
T
G
I
K
R
D
I
R
E
S
T
P
A
P
V
Sea Urchin
Strong. purpuratus
XP_794011
768
83924
P570
R
E
L
L
G
L
K
P
D
Q
P
K
K
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29056
596
66888
I427
S
G
H
F
Q
D
A
I
D
G
Y
S
L
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
86.4
82.7
N.A.
89.8
81.6
N.A.
N.A.
78.1
72.5
65.9
N.A.
42.5
43.4
32.4
46.3
Protein Similarity:
100
80
87
85.9
N.A.
93.3
86
N.A.
N.A.
87
84.7
77.6
N.A.
59.6
61.7
50
60.1
P-Site Identity:
100
100
0
26.6
N.A.
100
100
N.A.
N.A.
100
13.3
26.6
N.A.
20
13.3
6.6
20
P-Site Similarity:
100
100
26.6
40
N.A.
100
100
N.A.
N.A.
100
40
53.3
N.A.
26.6
46.6
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
15
0
0
15
0
0
0
0
0
0
% D
% Glu:
15
50
22
58
8
0
8
8
15
36
8
0
0
15
15
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
15
0
0
15
36
8
0
0
8
8
0
0
0
0
% G
% His:
0
0
8
8
8
0
0
0
0
0
36
0
0
0
0
% H
% Ile:
8
0
8
8
0
0
43
8
0
0
0
8
0
0
8
% I
% Lys:
36
29
43
15
8
29
22
22
58
15
8
65
15
58
43
% K
% Leu:
0
0
8
8
36
8
0
0
0
8
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
8
15
8
0
8
8
8
43
8
8
% P
% Gln:
0
0
0
0
8
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
8
0
8
0
15
0
0
15
0
0
15
15
22
8
8
% R
% Ser:
8
0
0
0
0
0
0
0
8
15
0
8
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
8
0
0
8
0
0
8
15
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
36
8
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _